neurophotonics centre


Frontiers in Neurophotonics Summer School 2015
4th International Frontiers in Neurophotonics Symposium 2015
Karl Deisseroth's plasmids available at the Neurophotonics Centre
Neurophotonics Training Program
An international Summer school on advanced optical imaging and photoactivation techniques October 3 - 6, 2015 | Québec city Learn more about our Neurophysics and Biophotonics training programs

Harnessing the power of photonics and related technologies to better understand the mysteries of the brain. A high caliber multidisciplinary team dedicated to the development of new tools to improve the diagnosis and treatment of brain diseases. Learn more


New biosensors from Robert Campbell’s laboratory

Dr. Robert Campbell, from the University of Alberta, recently published an article in Nature Methods in which he describes novel biosensors that change color in response to specific biological event.  This innovation is described in an article published by University of Alberta  titled: “Colour-changing proteins shed light on inner workings of live cells -Fluorescent proteins could signal new ways of treating everything from mental illness to diabetes and cancer.”

Read the full article at:University of Alberta news website

The original research article was published in Nature Methods:
Ding Y, Li J, Enterina JR, Shen Y, Zhang I, Tewson PH, Mo GC, Zhang J, Quinn AM, Hughes TE, Maysinger D, Alford SC, Zhang Y, Campbell RE. Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange. Nat Methods. 2015 Jan 26. doi: 10.1038/nmeth.3261. [Epub ahead of print] PubMed PMID:25622108.

La preuve par l’image – Scientific image contest

The ACFAS – Association francophone pour le savoir is holding its annual scientific image contest, and the prize for the 2015 International Year of Light will be awarded to images that illustrate the nature of light or the interaction between light and matter. Researchers are invited to submit their images by January 26th 2015. All the details are on the ACFAS website: Concours preuve par l’image 2015.

Neurophotonics Centre research featured on “Découverte”

decouverteResearchers Armen Saghatelyan, Paul and Yves De Koninck and Daniel Côté were recently featured on “Découverte”, the scientific television show presented by Radio-Canada.  The researchers explain the possibilities and promises of new neurophotonics approaches and technologies to better understand the brain, leading to major scientific breakthroughs.

View the segment here:

Canadian Neurophotonics Platform Lauch Meeting

The Neurophotonics Centre hosted the Launch meeting for the Canadian Neurophotonics Platform on December 16-17 2014 in Québec city.  The platform aims to develop, test and promote new neurophotonics tools using the power of optics and and photonics to serve research in neurosciences and the brain.

The lauch meeting was a great opportunity for platform members and important collaborators to prioritize the objectives and goals of the new platform.  You can read the announcement of the project here:

$3.3M from the Canadian Brain Research Fund for the Canadian Neurophotonics Platform

From left to right: Alan Fine, Ed Ruthazer, Tim Murphy, Yves De Koninck, Paul De Koninck, Jean-Claude Béïque, Katalin Toth, Mario Méthot

Second row: Daniel Côté, Robert Campbell, Marie-Ève Paquet, Isabelle Labonté

Absents at the time of the picture: André Longtin, Nizar Chetoui

Joined by video-conference: Jaideep Bains, Paul Wiseman

Diversity in synaptic vesicles allows transmission of different messages between neurons

Evstratova, Tóth and Chamberland

Evstratova, Tóth and Chamberland

Dr Katalin Tóth and her team recently published a paper in Nature Communications in which they explain, in part, how seemingly identical synaptic vesicles can be used to transmit different messages from one neuron to the next.

These researchers showed that vesicles derived from the AP-3-dependent endocytotic pathway were preferentially used in asynchronous release of neurotransmitter, a process involved in transmission of information   between specific brain regions important for processing spatial information. They also showed that animals lacking the AP-3-dependent recycling pathway had altered synaptic transmission in naturally occuring processes.
Read more in the original research article:

Evstratova A, Chamberland S, Faundez V, Tóth K. Vesicles derived via AP-3 dependent recycling contribute to asynchronous release and influence information transfer. Nature Communications, 2014 November 20 5:5530. doi: 10.1038/ncomms6530.


Master’s and PhD Projects Available

Professor Tigran Galstian, Canada Research Chair in Liquid Crystals and Behavioral Biophotonics,  is looking for passionate and committed students to engage in research projects (Masters and PhD) in the field of biophysics (including biophotonics). In particular, Prof. Galstian is interested in the self‐organization of matter in the form of naturally aligned molecular complexes to form biological membranes, the myelin, etc. (elements of “living” matter…). (more…)

Postdoctoral position available in Jean-Philippe Pin’s Lab Institute of Functional Genomics, Montpellier, France

A 30-month postdoctoral position funded by the ANR (Agence Nationale de la Recherche) is available starting after March 2015 in the research team ”Neuroreceptors, dynamics and function” (headed by J.-P. Pin). (more…)



BMC video screenshot BMC video screenshot BMC video screenshot BMC video screenshot BMC video screenshot
Frontiers in Neurophotonics Summer School Highlights video Beyond the diffraction barrier Visualizing the cellular progression of multiple sclerosis using multimodal video microscopy Recording the illuminated neuron Spatial Dynamics of Molecules in Learning Neuroblast migration in the adult brain


Evstratova A, Chamberland S, Faundez V, Tóth K. Vesicles derived via AP-3-dependent recycling contribute to asynchronous release and influence information transfer. Nat Commun. 2014 Nov 20;5:5530.PubMed

Zhou X, Hedberg J, Miyahara Y, Grutter P, Ishibashi K. Scanning gate imaging of two coupled quantum dots in single-walled carbon nanotubes. Nanotechnology. 2014 Dec 12;25(49):495703.PubMed

Haidarliu S, Kleinfeld D, Deschênes M, Ahissar E. The musculature that drives active touch by vibrissae and nose in mice. Anat Rec (Hoboken). 2014 Nov 18.PubMed

Doré K, Labrecque S, Tardif C, De Koninck P. FRET-FLIM Investigation of PSD95-NMDA Receptor Interaction in Dendritic Spines; Control by Calpain, CaMKII and Src Family Kinase. PLoS One. 2014 Nov 13;9(11):e112170.PubMed

Vangheluwe M, Liang F, Petit Y, Hée P, Ledemi Y, Thomas S, Fargin E, Cardinal T, Messaddeq Y, Canioni L, Vallée R. Enhancement of nanograting formation assisted by silver ions in a sodium gallophosphate glass. Opt Lett. 2014 Oct 1;39(19):5491-4.PubMed

Chamberland S, Evstratova A, Tóth K. Interplay between synchronization of multivesicular release and recruitment of additional release sites support short-term facilitation at hippocampal mossy fiber to CA3 pyramidal cells synapses. J Neurosci. 2014 Aug 13;34(33):11032-47.PubMed

Lavoie J, Marchand G, Cloutier Y, Hallé S, Nadeau S, Duchaine C, Pichette G. Evaluation of bioaerosol exposures during hospital bronchoscopy examinations. Environ Sci Process Impacts. 2014 Oct 2. [Epub ahead of print] PubMed

Deschênes M, Haidarliu S, Demers M, Moore J, Kleinfeld D, Ahissar E. Muscles involved in naris dilation and nose motion in rat. Anat Rec (Hoboken). 2014 Sep 25.PubMed

Lopez-Ayon GM, Liu HY, Xing S, Maria OM, LeDue JM, Bourque H, Grutter P, Komarova SV. Local membrane deformation and micro-injury lead to qualitatively different responses in osteoblasts. F1000Res. 2014 Jul 11;3:162.PubMed

Asselin J, Roy C, Boudreau D, Messaddeq Y, Bouchareb R, Mathieu P. Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH. Chem Commun (Camb). 2014 Sep 24. [Epub ahead of print] PubMed

Khazaei MR, Girouard MP, Alchini R, Ong Tone S, Shimada T, Bechstedt S, Cowan M, Guillet D, Wiseman PW, Brouhard G, Cloutier JF, Fournier AE. Collapsin Response Mediator Protein 4 regulates growth cone dynamics through the actin and microtubule cytoskeleton. J Biol Chem. 2014 Sep 15. pii: jbc.M114.570440. [Epub ahead of print] PubMed

Lavoie J, Hébert M, Beaulieu JM. Looking Beyond the Role of Glycogen Synthase Kinase-3 Genetic Expression on Electroretinogram Response: What About Lithium? Biol Psychiatry. 2014 Aug 1. pii: S0006-3223(14)00569-1.PubMed

Lorenzo LE, Magnussen C, Bailey AL, Louis MS, De Koninck Y, Ribeiro-da-Silva A. Spatial and temporal pattern of changes in the number of GAD65-immunoreactive inhibitory terminals in the rat superficial dorsal horn following peripheral nerve injury. Mol Pain. 2014 Sep 4;10:57.PubMed

Perepichka II, Mezour MA, Perepichka DF, Lennox RB. High thermal stability of block copolymer-capped Au and Cu nanoparticles. Chem Commun (Camb). 2014 Sep 11;50(80):11919-21.PubMed

Dumont G, Northoff G, Longtin A. Linear noise approximation for oscillations in a stochastic inhibitory network with delay. Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Jul;90(1-1):012702. Epub 2014 Jul 7. PubMed

Lachance M, Longtin A, Morris CE, Yu N, Joós B. Stimulation-induced ectopicity and propagation windows in model damaged axons. J Comput Neurosci. 2014 Aug 12. [Epub ahead of print] PubMed

Duchaine CS, Diorio C. Association between intake of sugar-sweetened beverages and circulating 25-hydroxyvitamin D concentration among premenopausal women. Nutrients. 2014 Jul 28;6(8):2987-99.PubMed

Aubé B, Lévesque SA, Paré A, Chamma E, Kébir H, Gorina R, Lécuyer MA, Alvarez JI, De Koninck Y, Engelhardt B, Prat A, Côté D, Lacroix S. Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases. J Immunol. 2014 Sep 1;193(5):2438-54.PubMed

Poulin H, Bruhova I, Timour Q, Theriault O, Beaulieu JM, Frassati D, Chahine M. Fluoxetine Blocks Nav1.5 Channels via a Mechanism Similar to That of Class 1 Antiarrhythmics. Mol Pharmacol. 2014 Oct;86(4):378-89.PubMed

Bonin RP, De Koninck Y. A spinal analog of memory reconsolidation enables reversal of hyperalgesia. Nat Neurosci. 2014 Aug;17(8):1043-5.PubMed

Moore JD, Deschênes M, Kurnikova A, Kleinfeld D. Activation and measurement of free whisking in the lightly anesthetized rodent. Nat Protoc. 2014 Aug;9(8):1792-802.PubMed

Skolianos G, Bernier M, Vallée R, Digonnet MJ. Observation of ~20 ns group delay in a low-loss apodized fiber Bragg grating. Opt Lett. 2014 Jul 1;39(13):3978-81.PubMed

Duchaine CS, Dumas I, Diorio C. Consumption of sweet foods and mammographic breast density: a cross-sectional study. BMC Public Health. 2014 Jun 26;14:554.PubMed

Petryszyn S, Beaulieu JM, Parent A, Parent M. Distribution and morphological characteristics of striatal interneurons expressing calretinin in mice: A comparison with human and nonhuman primates. J Chem Neuroanat. 2014 Sep;59-60:51-61.PubMed

Stidham SE, Chin SL, Dane EL, Grinstaff MW. Carboxylated glucuronic poly-amido-saccharides as protein stabilizing agents. J Am Chem Soc. 2014 Jul 9;136(27):9544-7.PubMed

Bergeron MJ, Castonguay A, De Koninck Y. [KCC2: a new therapeutical target for the treatment of neurological diseases]. Med Sci (Paris). 2014 May;30(5):514-7.PubMed

Lorenzo LE, Godin AG, Wang F, St-Louis M, Carbonetto S, Wiseman PW, Ribeiro-da-Silva A, De Koninck Y. Gephyrin Clusters Are Absent from Small Diameter Primary Afferent Terminals Despite the Presence of GABAA Receptors. J Neurosci. 2014 Jun 11;34(24):8300-17.PubMed

Thériault G, Cottet M, Castonguay A, McCarthy N, De Koninck Y. Extended two-photon microscopy in live samples with Bessel beams: steadier focus, faster volume scans, and simpler stereoscopic imaging. Front Cell Neurosci. 2014 May 20;8:139.PubMed

Arnspang EC, Koffman JS, Marlar S, Wiseman PW, Nejsum LN. Easy Measurement of Diffusion Coefficients of EGFP-tagged Plasma Membrane Proteins Using k-Space Image Correlation Spectroscopy. J Vis Exp. 2014 May 10;(87).PubMed

Iolov A, Ditlevsen S, Longtin A. Stochastic optimal control of single neuron spike trains. J Neural Eng. 2014 Jun 3;11(4):046004. [Epub ahead of print] PubMed

Haboucha A, Fortin V, Bernier M, Genest J, Messaddeq Y, Vallée R. Fiber Bragg grating stabilization of a passively mode-locked 2.8  μm Er3+: fluoride glass fiber laser. Opt Lett. 2014 Jun 1;39(11):3294-7.PubMed

Zou M, De Koninck P, Neve RL, Friedrich RW. Fast gene transfer into the adult zebrafish brain by herpes simplex virus 1 (HSV-1) and electroporation: methods and optogenetic applications. Front Neural Circuits. 2014 May 6;8:41.PubMed

Trudel L, Veillette M, Bonifait L, Duchaine C. Management of the 2012 Legionella crisis in Quebec City: need for a better communication between resources and knowledge transfer. Front Microbiol. 2014 May 5;5:182.PubMed

Zhu J, Chin J, Wängler C, Wängler B, Lennox RB, Schirrmacher R. Rapid (18)F-Labeling and Loading of PEGylated Gold Nanoparticles for in Vivo Applications. Bioconjug Chem. 2014 May 23. [Epub ahead of print] PubMed

Turgeon N, Toulouse MJ, Martel B, Moineau S, Duchaine C. Comparison of Five Bacteriophages as Models for Viral Aerosols Studies. Appl Environ Microbiol. 2014 May 2. [Epub ahead of print] PubMed

Kleinfeld D, Deschênes M, Wang F, Moore JD. More than a rhythm of life: breathing as a binder of orofacial sensation. Nat Neurosci. 2014 May;17(5):647-51.PubMed

Clarke SE, Longtin A, Maler L. A neural code for looming and receding motion is distributed over a population of electrosensory ON and OFF contrast cells. J Neurosci. 2014 Apr 16;34(16):5583-94.PubMed

Thivierge JP, Comas R, Longtin A. Attractor dynamics in local neuronal networks. Front Neural Circuits. 2014 Mar 20;8:22.PubMed

Bernier M, Fortin V, El-Amraoui M, Messaddeq Y, Vallée R. 3.77  μm fiber laser based on cascaded Raman gain in a chalcogenide glass fiber. Opt Lett. 2014 Apr 1;39(7):2052-5.PubMed

Paul W, Oliver D, Grütter P. Indentation-formed nanocontacts: an atomic-scale perspective. Phys Chem Chem Phys. 2014 Apr 9;16(18):8201-22.PubMed

Tyan L, Chamberland S, Magnin E, Camiré O, Francavilla R, David LS, Deisseroth K, Topolnik L. Dendritic inhibition provided by interneuron-specific cells controls the firing rate and timing of the hippocampal feedback inhibitory circuitry. J Neurosci. 2014 Mar 26;34(13):4534-47.PubMed

Jun JJ, Longtin A, Maler L. Long-term Behavioral Tracking of Freely Swimming Weakly Electric Fish. J Vis Exp. 2014 Mar 6;(85).PubMed

Camiré O, Topolnik L. Dendritic calcium nonlinearities switch the direction of synaptic plasticity in fast-spiking interneurons. J Neurosci. 2014 Mar 12;34(11):3864-77.PubMed

Marion S, Urs NM, Peterson SM, Sotnikova TD, Beaulieu JM, Gainetdinov RR, Caron MG. Dopamine D2 Receptor Relies upon PPM/PP2C Phosphatases to Dephosphorylate Huntingtin Protein. J Biol Chem. 2014 Mar 11. [Epub ahead of print] PubMed

Mejias JF, Payeur A, Selin E, Maler L, Longtin A. Subtractive, divisive and non-monotonic gain control in feedforward nets linearized by noise and delays. Front Comput Neurosci. 2014 Feb 25;8:19.PubMed

Spencer JA, Ferraro F, Roussakis E, Klein A, Wu J, Runnels JM, Zaher W, Mortensen LJ, Alt C, Turcotte R, Yusuf R, Côté D, Vinogradov SA, Scadden DT, Lin CP. Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature. 2014 Mar 2.PubMed

Duval S, Olivier M, Bernier M, Vallée R, Piché M. Ultrashort pulses from an all-fiber ring laser incorporating a pair of chirped fiber Bragg gratings. Opt Lett. 2014 Feb 15;39(4):989-92.PubMed

Mezour MA, Perepichka II, Zhu J, Lennox RB, Perepichka DF. Directing the Assembly of Gold Nanoparticles with Two-Dimensional Molecular Networks. ACS Nano. 2014 Feb 17. [Epub ahead of print] PubMed

Blais Lecours P, Marsolais D, Cormier Y, Berberi M, Haché C, Bourdages R, Duchaine C. Increased Prevalence of Methanosphaera stadtmanae in Inflammatory Bowel Diseases. PLoS One. 2014 Feb 3;9(2):e87734.PubMed

Krahe R, Maler L. Neural maps in the electrosensory system of weakly electric fish. Curr Opin Neurobiol. 2014 Feb;24C:13-21.PubMed

Ju J, Sun H, Sridharan A, Wang TJ, Wang C, Liu J, Li R, Xu Z, Chin SL. Laser-filament-induced snow formation in a subsaturated zone in a cloud chamber: Experimental and theoretical study. Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Dec;88(6-1):062803. Epub 2013 Dec 3. PubMed

Breton-Provencher V, Coté D, Saghatelyan A. Activity of the Principal Cells of the Olfactory Bulb Promotes a Structural Dynamic on the Distal Dendrites of Immature Adult-Born Granule Cells via Activation of NMDA Receptors. J Neurosci. 2014 Jan 29;34(5):1748-59.PubMed

Prescott SA, Ma Q, De Koninck Y. Normal and abnormal coding of somatosensory stimuli causing pain. Nat Neurosci. 2014 Feb;17(2):183-91.PubMed

Jowett N, Wöllmer W, Reimer R, Zustin J, Schumacher U, Wiseman PW, Mlynarek AM, Böttcher A, Dalchow CV, Lörincz BB, Knecht R, Miller RJ. Bone Ablation without Thermal or Acoustic Mechanical Injury via a Novel Picosecond Infrared Laser (PIRL). Otolaryngol Head Neck Surg. 2013 Dec 27. [Epub ahead of print] PubMed

Buggia-Prévot V, Fernandez CG, Udayar V, Vetrivel KS, Elie A, Roseman J, Sasse VA, Lefkow M, Meckler X, Bhattacharyya S, George M, Kar S, Bindokas VP, Parent AT, Rajendran L, Band H, Vassar R, Thinakaran G. A Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer's Disease Aβ Production. Cell Rep. 2013 Dec 26;5(6):1552-63.PubMed

Lavertu G, Côté SL, De Koninck Y. Enhancing K-Cl co-transport restores normal spinothalamic sensory coding in a neuropathic pain model. Brain. 2013 Dec 24. [Epub ahead of print] PubMed

Marceau V, Varin C, Brabec T, Piché M. Femtosecond 240-keV electron pulses from direct laser acceleration in a low-density gas. Phys Rev Lett. 2013 Nov 27;111(22):224801. Epub 2013 Nov 27. PubMed

Arnspang EC, Schwartzentruber J, Clausen MP, Wiseman PW, Lagerholm BC. Bridging the Gap between Single Molecule and Ensemble Methods for Measuring Lateral Dynamics in the Plasma Membrane. PLoS One. 2013 Dec 4;8(12):e78096.PubMed

Macdougall MJ, Fine A. The expression of long-term potentiation: reconciling the preists and the postivists. Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):20130135.PubMed

Daou I, Tuttle AH, Longo G, Wieskopf JS, Bonin RP, Ase AR, Wood JN, De Koninck Y, Ribeiro-da-Silva A, Mogil JS, Séguéla P. Remote optogenetic activation and sensitization of pain pathways in freely moving mice. J Neurosci. 2013 Nov 20;33(47):18631-40.PubMed

Recasens A, Dehay B, Bové J, Carballo-Carbajal I, Dovero S, Pérez A, Fernagut PO, Blesa J, Parent A, Perier C, Fariñas I, Obeso JA, Bezard E, Vila M. Lewy body extracts from parkinson's disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Ann Neurol. 2013 Nov 16.PubMed

Medvedev IO, Ramsey AJ, Masoud ST, Bermejo MK, Urs N, Sotnikova TD, Beaulieu JM, Gainetdinov RR, Salahpour A. D1 Dopamine Receptor Coupling to PLCβ Regulates Forward Locomotion in Mice. J Neurosci. 2013 Nov 13;33(46):18125-33.PubMed

Potvin-Trottier L, Chen L, Horwitz AR, Wiseman PW. A nu-space for ICS: characterization and application to measure protein transport in live cells. New J Phys. 2013 Aug;15.PubMed

Aven L, Paez-Cortez J, Achey R, Krishnan R, Ram-Mohan S, Cruikshank WW, Fine A, Ai X. An NT4/TrkB-dependent increase in innervation links early-life allergen exposure to persistent airway hyperreactivity. FASEB J. 2013 Nov 12. [Epub ahead of print] PubMed

Ba C, Bah ST, D'Auteuil M, Ashrit PV, Vallée R. Fabrication of High-Quality VO(2) Thin Films by Ion-Assisted Dual ac Magnetron Sputtering. ACS Appl Mater Interfaces. 2013 Nov 19. [Epub ahead of print] PubMed

Dury AY, El Fatimy R, Tremblay S, Rose TM, Côté J, De Koninck P, Khandjian EW. Nuclear Fragile X Mental Retardation Protein Is localized to Cajal Bodies. PLoS Genet. 2013 Oct;9(10):e1003890.PubMed

Del'guidice T, Lemay F, Lemasson M, Levasseur-Moreau J, Manta S, Etievant A, Escoffier G, Doré FY, Roman FS, Beaulieu JM. Stimulation of 5-HT(2C) Receptors Improves Cognitive Deficits Induced by Human Tryptophan Hydroxylase 2 Loss of Function Mutation. Neuropsychopharmacology. 2013 Nov 7.PubMed

Gasecka A, Daradich A, Dehez H, Piché M, Côté D. Resolution and contrast enhancement in coherent anti-Stokes Raman-scattering microscopy. Opt Lett. 2013 Nov 1;38(21):4510-3. PubMed

Paul W, Oliver D, Miyahara Y, Grütter P. Transient adhesion and conductance phenomena in initial nanoscale mechanical contacts between dissimilar metals. Nanotechnology. 2013 Nov 29;24(47):475704.PubMed

Goldman JS, Ashour MA, Magdesian MH, Tritsch NX, Harris SN, Christofi N, Chemali R, Stern YE, Thompson-Steckel G, Gris P, Glasgow SD, Grutter P, Bouchard JF, Ruthazer ES, Stellwagen D, Kennedy TE. Netrin-1 Promotes Excitatory Synaptogenesis between Cortical Neurons by Initiating Synapse Assembly. J Neurosci. 2013 Oct 30;33(44):17278-89.PubMed

Bégin S, Bélanger E, Laffray S, Aubé B, Chamma E, Bélisle J, Lacroix S, De Koninck Y, Côté D. Local assessment of myelin health in a multiple sclerosis mouse model using a 2D Fourier transform approach. Biomed Opt Express. 2013 Sep 5;4(10):2003-14.PubMed

Barbeau A, Swift JL, Godin AG, De Koninck Y, Wiseman PW, Beaulieu JM. Spatial intensity distribution analysis (SpIDA): a new tool for receptor tyrosine kinase activation and transactivation quantification. Methods Cell Biol. 2013;117:1-19. PubMed

Lavoie J, Hébert M, Beaulieu JM. Glycogen Synthase Kinase-3 Overexpression Replicates Electroretinogram Anomalies of Offspring at High Genetic Risk for Schizophrenia and Bipolar Disorder. Biol Psychiatry. 2013 Oct 16.PubMed

Gagnon M, Bergeron MJ, Lavertu G, Castonguay A, Tripathy S, Bonin RP, Perez-Sanchez J, Boudreau D, Wang B, Dumas L, Valade I, Bachand K, Jacob-Wagner M, Tardif C, Kianicka I, Isenring P, Attardo G, Coull JA, De Koninck Y. Chloride extrusion enhancers as novel therapeutics for neurological diseases. Nat Med. 2013 Oct 6.PubMed

Ferrini F, De Koninck Y. Microglia Control Neuronal Network Excitability via BDNF Signalling. Neural Plast. 2013;2013:429815. Epub 2013 Sep 5. Review. PubMed

Bonin RP, De Koninck Y. Restoring ionotropic inhibition as an analgesic strategy. Neurosci Lett. 2013 Sep 27.PubMed

Mejias JF, Marsat G, Bol K, Maler L, Longtin A. Learning contrast-invariant cancellation of redundant signals in neural systems. PLoS Comput Biol. 2013 Sep;9(9):e1003180.PubMed

Zhu J, Hiltz J, Lennox RB, Schirrmacher R. Chemical modification of single walled carbon nanotubes with tetrazine-tethered gold nanoparticles via a Diels-Alder reaction. Chem Commun (Camb). 2013 Nov 11;49(87):10275-10277. Epub 2013 Sep 24. PubMed

Harvey-Girard E, Maler L. Dendritic SK channels convert NMDA-R dependent LTD to Burst Timing Dependent Plasticity. J Neurophysiol. 2013 Sep 18. [Epub ahead of print] PubMed

Magnan F, Gagnon J, Fontaine FG, Boudreau D. Indium@silica core-shell nanoparticles as plasmonic enhancers of molecular luminescence in the UV region. Chem Commun (Camb). 2013 Sep 2. [Epub ahead of print] PubMed

Wiseman PW. Fluctuation Imaging Spiced Up with a Piece of PIE. Biophys J. 2013 Aug 20;105(4):831.PubMed

Brandão HB, Sangji H, Pandžić E, Bechstedt S, Brouhard GJ, Wiseman PW. Measuring ligand-receptor binding kinetics and dynamics using k-space image correlation spectroscopy. Methods. 2013 Aug 9.PubMed

Lavoie J, Hébert M, Beaulieu JM. Glycogen synthase kinase-3β haploinsufficiency lengthens the circadian locomotor activity period in mice. Behav Brain Res. 2013 Sep 15;253:262-5.PubMed

Del'guidice T, Lemasson M, Etiévant A, Manta S, Magno LA, Escoffier G, Roman FS, Beaulieu JM. Dissociations between cognitive and motor effects of psychostimulants and atomoxetine in hyperactive DAT-KO mice. Psychopharmacology (Berl). 2013 Aug 3. [Epub ahead of print] PubMed

Clarke SE, Naud R, Longtin A, Maler L. Speed-invariant encoding of looming object distance requires power law spike rate adaptation. Proc Natl Acad Sci U S A. 2013 Jul 29. [Epub ahead of print] PubMed

Arsenault D, Dal-Pan A, Tremblay C, Bennett DA, Guitton MJ, De Koninck Y, Tonegawa S, Calon F. PAK Inactivation Impairs Social Recognition in 3xTg-AD Mice without Increasing Brain Deposition of Tau and Aβ. J Neurosci. 2013 Jun 26;33(26):10729-10740. PubMed

Dehez H, Piché M, De Koninck Y. Resolution and contrast enhancement in laser scanning microscopy using dark beam imaging. Opt Express. 2013 Jul 1;21(13):15912-25.PubMed

Nagai Y, Carbajal JD, White JH, Sladek R, Grutter P, Lennox RB. An Electrochemically Controlled Microcantilever Biosensor. Langmuir. 2013 Jul 29. [Epub ahead of print] PubMed

Groh A, Bokor H, Mease RA, Plattner VM, Hangya B, Stroh A, Deschenes M, Acsády L. Convergence of Cortical and Sensory Driver Inputs on Single Thalamocortical Cells. Cereb Cortex. 2013 Jul 3. [Epub ahead of print] PubMed

Jun JJ, Longtin A, Maler L. Real-Time Localization of Moving Dipole Sources for Tracking Multiple Free-Swimming Weakly Electric Fish. PLoS One. 2013 Jun 21;8(6):e66596. Print 2013. PubMed

Chabot V, Miron Y, Charette PG, Grandbois M. Identification of the molecular mechanisms in cellular processes that elicit a surface plasmon resonance (SPR) response using simultaneous surface plasmon-enhanced fluorescence (SPEF) microscopy. Biosens Bioelectron. 2013 Jun 20;50C:125-131.PubMed

Bassett DC, Merle G, Lennox B, Rabiei R, Barthelat F, Grover LM, Barralet JE. Ultrasonic Phosphate Bonding of Nanoparticles. Adv Mater. 2013 Jul 26.PubMed

Parent A. Niels stensen: a 17th century scientist with a modern view of brain organization. Can J Neurol Sci. 2013 Jul;40(4):482-92. PubMed

David LS, Schachner M, Saghatelyan A. The extracellular matrix glycoprotein tenascin-R affects adult but not developmental neurogenesis in the olfactory bulb. J Neurosci. 2013 Jun 19;33(25):10324-39.PubMed

Latapy C, Beaulieu JM. β-Arrestins in the Central Nervous System. Prog Mol Biol Transl Sci. 2013;118:267-95.PubMed

Rappaz B, Wiseman PW. Image correlation spectroscopy for measurements of particle densities and colocalization. Curr Protoc Cell Biol. 2013 Jun;Chapter 4:Unit4.27.PubMed

Chubak J, Yu O, Buist DS, Wirtz HS, Boudreau DM. Time Scale in Follow-up Studies: Considering Disease Prognosis. Epidemiology. 2013 Jul;24(4):628-9.PubMed

Zhou Y, Boudreau DM, Freedman AN. Trends in the use of aspirin and nonsteroidal anti-inflammatory drugs in the general U.S. population. Pharmacoepidemiol Drug Saf. 2013 May 30.PubMed

Borodin AV, Panov NA, Kosareva OG, Andreeva VA, Esaulkov MN, Makarov VA, Shkurinov AP, Chin SL, Zhang XC. Transformation of terahertz spectra emitted from dual-frequency femtosecond pulse interaction in gases. Opt Lett. 2013 Jun 1;38(11):1906-8.PubMed

Deschenes MR, Hurst TE, Ramser AE, Sherman EG. Pre- to post-synaptic relationships of the neuromuscular junction are held constant across age and muscle fiber type. Dev Neurobiol. 2013 May 22.PubMed

Tripathy U, Giguère-Bisson M, Sangji MH, Bellemare MJ, Bohle DS, Georges E,Wiseman PW. Optimization of malaria detection based on third harmonic generation imaging of hemozoin. Anal Bioanal Chem. 2013 Jun;405(16):5431-40.PubMed

Miri AK, Heris HK, Tripathy U, Wiseman PW, Mongeau L. Microstructural characterization of vocal folds toward a strain-energy model of collagen remodeling. Acta Biomater. 2013 May 3.PubMed

Tekiel A, Miyahara Y, Topple JM, Grutter P. Room-temperature single-electron charging detected by electrostatic force microscopy. ACS Nano. 2013 May 28;7(5):4683-90.PubMed

Moore JD, Deschênes M, Furuta T, Huber D, Smear MC, Demers M, Kleinfeld D. Hierarchy of orofacial rhythms revealed through whisking and breathing. Nature. 2013 Apr 28.PubMed

Doyon N, Ferrini F, Gagnon M, De Koninck Y. Treating pathological pain: is KCC2 the key to the gate? Expert Rev Neurother. 2013 May;13(5):469-71.PubMed

Tripathy U, Giguère-Bisson M, Sangji MH, Bellemare MJ, Bohle DS, Georges E, Wiseman PW. Optimization of malaria detection based on third harmonic generation imaging of hemozoin. Anal Bioanal Chem. 2013 May 7. PubMed

Miri AK, Heris HK, Tripathy U, Wiseman PW, Mongeau L. Microstructural Characterization of Vocal Folds toward a Strain-Energy Model of Collagen Remodeling. Acta Biomater. 2013 May 2.PubMed

Tekiel A, Miyahara Y, Topple JM, Grutter P. Room-Temperature Single-Electron Charging Detected by Electrostatic Force Microscopy. ACS Nano. 2013 May 8. [Epub ahead of print] PubMed

Thériault G, De Koninck Y, McCarthy N. Extended depth of field microscopy for rapid volumetric two-photon imaging. Opt Express. 2013 Apr 22;21(8):10095-104.PubMed

Sun H, Liu J, Wang C, Ju J, Wang Z, Wang W, Ge X, Li C, Chin SL, Li R, Xu Z. Laser filamentation induced air-flow motion in a diffusion cloud chamber. Opt Express. 2013 Apr 22;21(8):9255-66.PubMed

Ricoult SG, Pla-Roca M, Safavieh R, Lopez-Ayon GM, Grütter P, Kennedy TE, Juncker D. Large Dynamic Range Digital Nanodot Gradients of Biomolecules Made by Low-Cost Nanocontact Printing for Cell Haptotaxis. Small. 2013 Apr 18.PubMed

Braubach OR, Miyasaka N, Koide T, Yoshihara Y, Croll RP, Fine A. Experience-Dependent versus Experience-Independent Postembryonic Development of Distinct Groups of Zebrafish Olfactory Glomeruli. J Neurosci. 2013 Apr 17;33(16):6905-16.PubMed

Paul W, Oliver D, Miyahara Y, Grütter PH. Minimum threshold for incipient plasticity in the atomic-scale nanoindentation of au(111). Phys Rev Lett. 2013 Mar 29;110(13):135506. Epub 2013 Mar 27. PubMed

Ni J, Chu W, Jing C, Zhang H, Zeng B, Yao J, Li G, Xie H, Zhang C, Xu H, Chin SL, Cheng Y, Xu Z. Identification of the physical mechanism of generation of coherent N2 + emissions in air by femtosecond laser excitation. Opt Express. 2013 Apr 8;21(7):8746-52.PubMed

Mercier LG, Leclerc M. Direct (Hetero)Arylation: A New Tool for Polymer Chemists. Acc Chem Res. 2013 Apr 1. [Epub ahead of print] PubMed

Plante MP, Bérubé E, Bissonnette L, Bergeron MG, Leclerc M. Polythiophene Biosensor for Rapid Detection of Microbial Particles in Water. ACS Appl Mater Interfaces. 2013 Apr 8. [Epub ahead of print] PubMed

Kulldorff M, Dashevsky I, Avery TR, Chan AK, Davis RL, Graham D, Platt R, Andrade SE, Boudreau D, Gunter MJ, Herrinton LJ, Pawloski PA, Raebel MA, Roblin D, Brown JS. Drug safety data mining with a tree-based scan statistic. Pharmacoepidemiol Drug Saf. 2013 May;22(5):517-23.PubMed

Charlebois I, Gravel C, Arrad N, Boissinot M, Bergeron MG, Leclerc M. Impact of DNA Sequence and Oligonucleotide Length on a Polythiophene-Based Fluorescent DNA Biosensor. Macromol Biosci. 2013 Mar 19.PubMed

Marceau V, Varin C, Piché M. Validity of the paraxial approximation for electron acceleration with radially polarized laser beams. Opt Lett. 2013 Mar 15;38(6):821-3.PubMed

Dufour S, Lavertu G, Dufour-Beauséjour S, Juneau-Fecteau A, Calakos N, Deschênes M, Vallée R, De Koninck Y. A multimodal micro-optrode combining field and single unit recording, multispectral detection and photolabeling capabilities. PLoS One. 2013;8(2):e57703.PubMed

Jackson R, Braubach OR, Bilkey J, Zhang J, Akimenko MA, Fine A, Croll RP, Jonz MG. Expression of sall4 in taste buds of zebrafish. Dev Neurobiol. 2013 Feb 28.PubMed

Chakraborty A, Latapy C, Xu J, Snyder SH, Beaulieu JM. Inositol hexakisphosphate kinase-1 regulates behavioral responses via GSK3 signaling pathways. Mol Psychiatry. 2013 Feb 26.PubMed

Labuda A, Kobayashi K, Suzuki K, Yamada H, Grütter P. Monotonic damping in nanoscopic hydration experiments. Phys Rev Lett. 2013 Feb 8;110(6):066102. Epub 2013 Feb 7. PubMed

Harvey-Girard E, Giassi AC, Ellis W, Maler L. Expression of the cannabinoid CB1 receptor in the gymnotiform fish brain and its implications for the organization of the teleost pallium. J Comp Neurol. 2013 Mar 1;521(4):949-75.PubMed

Sirko S, Behrendt G, Johansson PA, Tripathi P, Costa M, Bek S, Heinrich C, Tiedt S, Colak D, Dichgans M, Fischer IR, Plesnila N, Staufenbiel M, Haass C, Snapyan M, Saghatelyan A, Tsai LH, Fischer A, Grobe K, Dimou L, Götz M. Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog glia. Cell Stem Cell. 2013 Apr 4;12(4):426-39.PubMed

Eid L, Champigny MF, Parent A, Parent M. Quantitative and ultrastructural study of serotonin innervation of the globus pallidus in squirrel monkeys. Eur J Neurosci. 2013 Feb 25.PubMed

Grade S, Weng YC, Snapyan M, Kriz J, Malva JO, Saghatelyan A. Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatum. PLoS One. 2013;8(1):e55039.PubMed

Barbeau A, Godin AG, Swift JL, De Koninck Y, Wiseman PW, Beaulieu JM. Quantification of receptor tyrosine kinase activation and transactivation by G-protein-coupled receptors using spatial intensity distribution analysis (SpIDA). Methods Enzymol. 2013;522:109-31.PubMed

Bories C, Husson Z, Guitton MJ, De Koninck Y. Differential balance of prefrontal synaptic activity in successful versus unsuccessful cognitive aging. J Neurosci. 2013 Jan 23;33(4):1344-56.PubMed

Lavoie J, Illiano P, Sotnikova TD, Gainetdinov RR, Beaulieu JM, Hébert M. The Electroretinogram as a Biomarker of Central Dopamine and Serotonin: Potential Relevance to Psychiatric Disorders. Biol Psychiatry. 2013 Jan 7.PubMed

Milette J, Toader V, Soulé ER, Lennox RB, Rey AD, Reven L. A molecular and thermodynamic view of the assembly of gold nanoparticles in nematic liquid crystal. Langmuir. 2013 Jan 29;29(4):1258-63.PubMed

Ferrini F, Trang T, Mattioli TA, Laffray S, Del'Guidice T, Lorenzo LE, Castonguay A, Doyon N, Zhang W, Godin AG, Mohr D, Beggs S, Vandal K, Beaulieu JM, Cahill CM, Salter MW, De Koninck Y. Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis. Nat Neurosci. 2013 Feb;16(2):183-92.PubMed

Wiseman PW. Image correlation spectroscopy: mapping correlations in space, time, and reciprocal space. Methods Enzymol. 2013;518:245-67.PubMed

Lefebvre J, Hutt A, Leblanc VG, Longtin A. Reduced dynamics for delayed systems with harmonic or stochastic forcing. Chaos. 2012 Dec;22(4):043121.PubMed

Saliminia A, Bérubé JP, Vallée R. Refractive index-modified structures in glass written by 266nm fs laser pulses. Opt Express. 2012 Dec 3;20(25):27410-9.PubMed

Tekiel A, Topple J, Miyahara Y, Grütter P. Layer-by-layer growth of sodium chloride overlayers on an Fe(001)-p(1 × 1)O surface. Nanotechnology. 2012 Dec 21;23(50):505602.PubMed

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