Title | Formula for Unsilencing Plasticity: Spike with GABA. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Kesner, Philip, Delphine Gobert, and Edward S. Ruthazer |
Journal | Neuron |
Volume | 87 |
Issue | 5 |
Pagination | 915-7 |
Date Published | 2015 Sep 2 |
ISSN | 1097-4199 |
Keywords | Action Potentials, Animals, Neuronal Plasticity, Neurons, Superior Colliculi, Vision, Ocular |
Abstract | A complication for developmental plasticity mechanisms like spike-timing-dependent plasticity (STDP) is that immature postsynaptic neurons may lack sufficient input to fire action potentials. In this issue, van Rheede et al. (2015) report an activity-dependent mechanism that converts non-spiking cells into spiking neurons, priming them for further plasticity. |
DOI | 10.1016/j.neuron.2015.08.016 |
Alternate Journal | Neuron |
PubMed ID | 26335639 |