Yves De Koninck, Ph.D.
Studies nervous signal transmission using state of the art techniques with the aim of alleviating chronic pain
Director | Neurophotonics Center
Project Leader | Canadian Neurophotonics Platform
Canada Research Chair in Chronic Pain and Related Brain Disorders - Tier 1
Université Laval Foundation Research Chair on brain and pain
Professor of Psychiatry & Neuroscience - Université Laval
Scientific Director, CERVO Brain Research Centre
Director of Research of the Centre intégré universitaire de santé et de services sociaux (CIUSSS) de la Capitale-Nationale
Director, Neurophotonics Centre
Founder - Quebec Pain Research Network
Yves de Koninck studies the the physiological, pharmacological and anatomical bases of the transmission of signals between neurons. His recent research interests include:
- The integration of sensory signals in the spinal cord and the brain, and in particular the cellular changes associated with the development of chronic pain and other pathological conditions of the central nervous system.
- Mathematical modeling of the functions of neurons.
- The development of new imaging techniques to study the neuronal function.
- Changes in synaptic physiology during aging.
His team uses a wide array of approaches, including electrophysiological recording in vivo (micro-optrodes) and in vitro (patch clamp in slices), multiphoton and other non-linear imaging techniques, time-resolved fluorescence microscopy, in vivo optogenetics, tissue-based biochemical analysis, neural tracing and immunocytochemistry, and computational approaches.
Learn more about Dr De Koninck's research interests on his research profile on the CERVO Brain Research Centre website